Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens.
نویسندگان
چکیده
Two new 20,24-bishomo-25-norscalaranes, compounds 1 and 2, and two new and two known 20,24-bishomoscalaranes, compounds 3-6, have been isolated from the Indonesian marine sponge Carteriospongia foliascens. The structures of 1-6 were determined by spectroscopic analysis. Compounds 1 and 3-6 inhibit RCE-protease activity.
منابع مشابه
Cytotoxic scalarane sesterterpenoids from the South China Sea sponge Carteriospongia foliascens.
Eleven new scalarane sesterterpenoids, including three 20,24-bishomo-25-norscalaranes, carteriofenones A–C (1–3), and eight 20,24-bishomoscalaranes, carteriofenones D–K (4–11), along with two known analogues (12 and 13), were obtained from the marine sponge Carteriospongia foliascens collected from the South China Sea. Their planar structures and relative configurations were elucidated by exten...
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ورودعنوان ژورنال:
- Journal of natural products
دوره 72 6 شماره
صفحات -
تاریخ انتشار 2009